Adrenal cortex–medulla interactions in adaptation to stress and disease

Journal article

S. Bornstein, I. Berger, L. Scriba, A. Santambrogio, C. Steenblock
Current Opinion in Endocrine and Metabolic Research, 2019

Semantic Scholar DOI

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APA Click to copy
Bornstein, S., Berger, I., Scriba, L., Santambrogio, A., & Steenblock, C. (2019). Adrenal cortex–medulla interactions in adaptation to stress and disease. Current Opinion in Endocrine and Metabolic Research.

Chicago/Turabian Click to copy
Bornstein, S., I. Berger, L. Scriba, A. Santambrogio, and C. Steenblock. “Adrenal Cortex–Medulla Interactions in Adaptation to Stress and Disease.” Current Opinion in Endocrine and Metabolic Research (2019).

MLA Click to copy
Bornstein, S., et al. “Adrenal Cortex–Medulla Interactions in Adaptation to Stress and Disease.” Current Opinion in Endocrine and Metabolic Research, 2019.

BibTeX Click to copy

@article{s2019a,
  title = {Adrenal cortex–medulla interactions in adaptation to stress and disease},
  year = {2019},
  journal = {Current Opinion in Endocrine and Metabolic Research},
  author = {Bornstein, S. and Berger, I. and Scriba, L. and Santambrogio, A. and Steenblock, C.}
}

Abstract

Abstract The adrenal gland plays a major role in response to physiological challenges and is able to adapt to homeostatic alterations. The adrenal is composed of two different tissue types in a bidirectional connection, the medulla, and the cortex. Already during adrenal organogenesis, close interactions between the two parts are necessary for the differentiation and morphogenesis of the gland. Moreover, communication between the cortex and the medulla ensures a regular function of the adult adrenal. Proper adaptation is of particular importance because dysregulation of the stress system is the cause of various diseases. In the current review, we summarize the significant progress made in the understanding of the cortical–chromaffin communications in stress and disease during the last couple of years.